| Champ: | Roger Federer |
| Runner: |  Rafael Nadal |
| Score: | 6–3, 6–4 |
| Draw: | 96 (12 / 5) |
| Seeds: | 32 |
| Before Name: | Miami Open – Men's singles |
| After Name: | Miami Open – Men's singles |
See main article: 2017 Miami Open.
Roger Federer defeated Rafael Nadal in the final, 6–3, 6–4 to win the men's singles tennis title at the 2017 Miami Open. It was Federer's third Miami Open title, and he claimed his third Sunshine Double with the win. It was also the fourth straight year the men's champion completed the Sunshine Double, after Novak Djokovic did so between 2014 and 2016. Federer saved two match points en route to the title, in the quarterfinals against Tomáš Berdych. It was Nadal's fifth runner-up finish without winning the title.
Djokovic was the three-time reigning champion, but withdrew before the tournament due to a right elbow injury. Reigning world No. 1 Andy Murray also withdrew before the tournament due to a right elbow injury. This marked the first time since 1990, when the Masters tournaments were created, that neither the world No. 1 nor No. 2 played the Miami Open, and the first time since the 2005 Madrid Masters that neither Djokovic nor Murray featured in the main draw of a Masters event.[1]
Stan Wawrinka was the first player other than a member of the Big Four to be the top seed at a Masters 1000 event since Andy Roddick at the 2005 Indian Wells Masters.[2]
All seeds receive a bye into the second round.
