| Champ: |  Alfie Hewett |
| Runner: |  Gustavo Fernández |
| Score: | 0–6, 7–6(11–9), 6–2 |
See main article: 2017 French Open.
Alfie Hewett defeated the defending champion Gustavo Fernández in the final, 0–6, 7–6(11–9), 6–2 to win the men's singles wheelchair tennis title at the 2017 French Open. It was his first major singles title.