| Champ: |  Rafael Nadal |
| Runner: |  Dominic Thiem |
| Score: | 6–4, 6–1 |
| Type: | singles doubles |
| Draw: | 48 (6 / 5) |
| Seeds: | 16 |
| Before Name: | Barcelona Open Banc Sabadell – Singles |
| After Name: | Barcelona Open Banco Sabadell – Singles |
| Main Name: | Barcelona Open (tennis) Barcelona Open |
See main article: 2017 Barcelona Open Banco Sabadell.
Defending champion Rafael Nadal defeated Dominic Thiem in the final, 6–4, 6–1 to win the singles tennis title at the 2017 Barcelona Open. It was his record-extending tenth Barcelona Open title.
All seeds receive a bye into the second round.