See main article: 2017–18 Women's EHF Champions League. This article describes the knockout stage of the 2017–18 Women's EHF Champions League.[1]
The top four placed teams from each of the two main round groups advanced to the knockout stage.
| Group | width=200 | First place | width=200 | Second place | width=200 | Third place | width=200 | Fourth place |
|---|---|---|---|---|---|---|---|---|
| 1 |  Győri Audi ETO KC |  Rostov-Don |  CSM București | FC Midtjylland | ||||
| 2 |  HC Vardar |  Metz Handball | FTC-Rail Cargo Hungaria |  ŽRK Budućnost |
The first-placed team of each group faces the fourth-placed team, and the second-placed team will play against the third-placed team from the other group. After that a draw will be held to determine the pairings for the final four.
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Győri ETO won 56–48 on aggregate.----Rostov-Don won 63–51 on aggregate.----CSM București won 54–48 on aggregate.----HC Vardar won 56–48 on aggregate.
The final four was held at the László Papp Budapest Sports Arena in Budapest, Hungary on 12 and 13 May 2018. The draw took place on 17 April 2018.[2] [3]
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