| Date: | 12–18 September |
| Edition: | 2nd |
| Category: | ITF Women's Circuit |
| Venue: | Hengqin International Tennis Center |
| Location: | Zhuhai, China |
| Prize Money: | $50,000 |
| Champs: |  Olga Govortsova |
| Champd: |  Ankita Raina /  Emily Webley-Smith |
| After Name: | Zhuhai Open |
The 2016 Zhuhai ITF Women's Pro Circuit was a professional tennis tournament played on outdoor hard courts. It was the 2nd edition of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $50,000 in prize money. It took place at the Hengqin International Tennis Center in Zhuhai, China, on 12–18 September 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Russian Federation | Elizaveta Kulichkova | 115 | 1 | |
| Tatjana Maria | 121 | 2 | ||
 China | Liu Fangzhou | 152 | 3 | |
 Uzbekistan | Nigina Abduraimova | 172 | 4 | |
 Turkey | İpek Soylu | 190 | 5 | |
| Russian Federation | Anastasia Pivovarova | 191 | 6 | |
| Chang Kai-chen | 198 | 7 | ||
| Lee Ya-hsuan | 203 | 8 |
The following player received a wildcard into the singles main draw:
Cao Siqi Wang Yan You Xiaodi Zhang YingThe following players received entry from the qualifying draw:
See main article: 2016 Zhuhai ITF Women's Pro Circuit – Singles.
Olga Govortsova def. İpek Soylu, 6–1, 6–2See main article: 2016 Zhuhai ITF Women's Pro Circuit – Doubles.
Ankita Raina / Emily Webley-Smith def. Guo Hanyu / Jiang Xinyu, 6–4, 6–4
