| Date: | 28 March–3 April |
| Edition: | 8th |
| Category: | ITF Women's Circuit |
| Location: | Osprey, Florida, United States |
| Prize Money: | $50,000 |
| Champs: |  Madison Brengle |
| Champd: | Asia Muhammad / Taylor Townsend |
The 2016 Wilde Lexus Women's USTA Pro Circuit Event was a professional tennis tournament played on outdoor clay courts. It was the eighth edition of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $50,000 in prize money. It took place in Osprey, Florida, United States, on 28 March–3 April 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Madison Brengle | 60 | 1 | |
 Japan | Kurumi Nara | 78 | 2 | |
| Anastasija Sevastova | 88 | 3 | ||
 Spain | Lara Arruabarrena | 89 | 4 | |
| Tatjana Maria | 92 | 5 | ||
 Italy | Francesca Schiavone | 105 | 6 | |
 Russian Federation | Evgeniya Rodina | 107 | 7 | |
| United States | Samantha Crawford | 109 | 8 |
The following players received wildcards into the singles main draw:
Jennifer Brady Sophia Edwards Jamie LoebThe following players received entry from the qualifying draw:
The following player received an entry by a lucky loser spot:
See main article: 2016 Wilde Lexus Women's USTA Pro Circuit Event – Singles.
Madison Brengle def. Lara Arruabarrena, 4–6, 6–4, 6–3See main article: 2016 Wilde Lexus Women's USTA Pro Circuit Event – Doubles.
Asia Muhammad / Taylor Townsend def. Louisa Chirico / Katerina Stewart, 6–1, 6–7(5–7), [10–4]