| Competition: | Campeonato Nacional Clausura Scotiabank |
| Dates: | 15 January – 15 May 2016 |
| Season: | 2015–16 |
| Winners: | Universidad Católica (11th title) |
| Relegated: | San Marcos de Arica Unión La Calera |
| Continentalcup1: | 2017 Copa Libertadores |
| Continentalcup1 Qualifiers: | Universidad Católica |
| Continentalcup2: | 2016 Copa Sudamericana |
| Continentalcup2 Qualifiers: | O'Higgins Palestino U. de Concepción |
| League Topscorer: | Nicolás Castillo (11 goals) |
| Biggest Home Win: | U. de Chile 8–1 O'Higgins (24 January) |
| Highest Attendance: | 31,023 U. de Chile 0–0 Colo-Colo (20 March) |
| Attendance: | 622,725 |
| Average Attendance: | 5,189 |
| Matches: | 120 |
| Total Goals: | 356 |
| Prevseason: | 2015–A |
| Nextseason: | 2016–A |
The 2016 Campeonato Nacional Clausura Scotiabank was the 98th Chilean League top flight, in which Universidad Católica won its 11th league title.
| ANT | AUD | CSA | COL | HUA | IQU | OHI | PAL | SLU | SMA | LCA | UCA | UCH | UCO | UES | SWA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antofagasta | 1–2 | 2–1 | 3–0 | 2–3 | 0–2 | 1–1 | 3–1 | 1–1 | ||||||||
| Audax | 0–1 | 0–3 | 2–2 | 1–0 | 0–0 | 0–0 | 1–1 | |||||||||
| Cobresal | 3–2 | 2–3 | 2–3 | 0–0 | 0–0 | 1–4 | 1–0 | |||||||||
| Colo-Colo | 2–1 | 1–0 | 1–1 | 1–3 | 2–0 | 3–0 | 1–1 | 2–1 | ||||||||
| Huachipato | 0–3 | 0–1 | 3–3 | 1–1 | 4–2 | 3–0 | 3–3 | 3–2 | ||||||||
| Iquique | 1–1 | 1–1 | 0–0 | 1–1 | 1–3 | 2–3 | 1–2 | |||||||||
| O'Higgins | 3–0 | 0–0 | 1–1 | 4–3 | 4–0 | 4–3 | 1–2 | 0–0 | ||||||||
| Palestino | 0–2 | 2–1 | 1–1 | 2–2 | 2–2 | 0–1 | 2–1 | 3–0 | ||||||||
| San Luis | 0–0 | 3–1 | 1–1 | 3–1 | 1–0 | 1–1 | 2–2 | |||||||||
| San Marcos | 0–2 | 1–0 | 0–1 | 0–1 | 2–3 | 0–1 | 3–2 | 0–2 | ||||||||
| La Calera | 0–1 | 1–2 | 2–4 | 1–1 | 1–2 | 2–1 | 3–3 | |||||||||
| U. Católica | 2–1 | 2–1 | 1–0 | 2–2 | 2–2 | 2–1 | 4–2 | 4–2 | ||||||||
| U. Chile | 2–2 | 0–0 | 2–1 | 8–1 | 0–0 | 2–2 | 1–3 | |||||||||
| U. Concepción | 2–1 | 2–0 | 0–2 | 2–1 | 2–4 | 3–1 | 1–0 | |||||||||
| U. Española | 0–2 | 1–1 | 1–1 | 3–1 | 1–1 | 0–0 | 2–2 | |||||||||
| S. Wanderers | 1–1 | 2–2 | 3–1 | 3–1 | 0–0 | 3–1 | 5–4 | |||||||||
Following the conclusion of the regular season, the teams placed 2nd to 5th qualify for the Liguilla in order to determine the "Chile 2" spot to the 2016 Copa Sudamericana. However, teams that already played the 2016 Copa Libertadores (from second stage onwards) and both finalists of Copa Chile are ineligible to compete in the Liguilla.[1] These teams are the following:
O'Higgins won 3–2 on aggregate.----
0–0 on aggregate. Santiago Wanderers won 4–3 on penalties.
O'Higgins won 1–0 on aggregate and qualified for the 2016 Copa Sudamericana.