| Competition: | Campeonato Nacional Apertura Scotiabank |
| Dates: | 29 July – 10 December 2016 |
| Season: | 2016–17 |
| Winners: | Universidad Católica (12th title) |
| Continentalcup1: | 2017 Copa Libertadores |
| Continentalcup1 Qualifiers: | Deportes Iquique Unión Española (playoff winners) Colo-Colo (Cup champions) |
| Continentalcup2: | 2017 Copa Sudamericana |
| Continentalcup2 Qualifiers: | Palestino Universidad de Chile O'Higgins (playoff losers) Everton (Cup runners-up) |
| League Topscorer: | Nicolás Castillo (13 goals) |
| Biggest Home Win: | Palestino 5–1 D. Antofagasta (15 October) |
| Biggest Away Win: | D. Iquique 2–6 U. Católica (4 December) |
| Highest Attendance: | 44,789 U. de Chile 2–2 D. Iquique (5 November) |
| Attendance: | 853,851 |
| Average Attendance: | 7,115 |
| Matches: | 120 |
| Total Goals: | 347 |
| Prevseason: | 2016–C |
| Nextseason: | 2017–C |
The 2016 Campeonato Nacional Apertura Scotiabank was the 99th Chilean League top flight, in which Universidad Católica won its 12th league title, their second in a row.
The pre-Copa Libertadores playoff was played between:[1]
The winner qualified for the 2017 Copa Libertadores second stage, while the loser qualified for the 2017 Copa Sudamericana first stage.
| Rank | Name | Club | Goals | |
|---|---|---|---|---|
| align=center | 1 | Nicolás Castillo | Universidad Católica | 13 |
| 2 |  Leandro Benegas | Palestino | 10 | |
| Diego Churín | Unión Española | 10 | ||
| Esteban Paredes | Colo-Colo | 10 | ||
| 5 | Diego Buonanotte | Universidad Católica | 8 | |
| Cristian Insaurralde | O'Higgins | 8 | ||
| Carlos Salom | Unión Española | 8 |
Source: Soccerway