| Year: | 2016 |
| Team: | Texas Southern Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Division: | West Division |
| Short Conf: | SWAC |
| Record: | 4–7 |
| Conf Record: | 4–5 |
| Head Coach: | Michael Haywood |
| Hc Year: | 1st |
| Off Coach: | Greg Gregory |
| Oc Year: | 1st |
| Def Coach: | Tom Anthony |
| Dc Year: | 1st |
| Stadium: | BBVA Compass Stadium |
The 2016 Texas Southern Tigers football team represented Texas Southern University a member of the West Division of the Southwestern Athletic Conference (SWAC) during the 2016 NCAA Division I FCS football season. Led by first-year head coach Michael Haywood, the Tigers compiled an overall record of 4–7 with a mark of 4–5 in conference play, placing fourth in the SWAC's West Division. Texas Southern played home games at BBVA Compass Stadium in Houston.