The 2016 Shanghai Challenger was a professional tennis tournament played on hard courts. It was the sixth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Shanghai, China between 5 and 12 September 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Australia | Jordan Thompson | 91 | 1 | |
 Japan | Tatsuma Ito | 129 | 2 | |
| Japan | Go Soeda | 147 | 3 | |
| Henri Laaksonen | 161 | 4 | ||
 Italy | Luca Vanni | 164 | 5 | |
| Jason Jung | 169 | 6 | ||
 Russian Federation | Alexander Kudryavtsev | 170 | 7 | |
 China | Zhang Ze | 174 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw with a protected ranking:
The following player entered the singles main draw as an alternate"
The following players received entry from the qualifying draw:
Yasutaka Uchiyama Xia Zihao Shuichi SekiguchiSee main article: 2016 Shanghai Challenger – Singles.
See main article: 2016 Shanghai Challenger – Doubles.
Gao Xin / Li Zhe 7–6(8–6), 5–7, [10–0]