| Score: | 5–7, 7–6(7–4), [10–8] |
| Type: | singles doubles |
See main article: 2016 Savannah Challenger.
Guillermo Durán and Horacio Zeballos were the defending champions but chose not to participate.
Brian Baker and Ryan Harrison won the title, defeating Purav Raja and Divij Sharan 5–7, 7–6(7–4), [10–8] in the final.