| Score: | 6–3, 6–4 |
| Type: | singles doubles |
See main article: article and 2016 Santiago Challenger.
Guillermo Durán and Máximo González were the defending champions but only González chose to defend his title, partnering Sergio Galdós. González lost in the final to Julio Peralta and Horacio Zeballos.
Peralta and Zeballos won the title after defeating Galdós and González 6–3, 6–4 in the final.