The 2016 Santaizi ATP Challenger was a professional tennis tournament played on indoor carpet courts. It was the third edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Taipei, Taiwan between 25 April and 1 May.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Lithuania | Ričardas Berankis | 62 | 1 | |
 Australia | Sam Groth | 80 | 2 | |
 Japan | Tatsuma Ito | 103 | 3 | |
| Japan | Yūichi Sugita | 111 | 4 | |
 Ukraine | Sergiy Stakhovsky | 122 | 5 | |
 United Kingdom | Daniel Evans | 124 | 6 | |
| Japan | Go Soeda | 128 | 7 | |
 Russian Federation | Konstantin Kravchuk | 129 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Marinko Matosevic Dayne Kelly Shuichi Sekiguchi Yuya KibiSee main article: 2016 Santaizi ATP Challenger – Singles.
Daniel Evans def. Konstantin Kravchuk, 3–6, 6–4, 6–4See main article: 2016 Santaizi ATP Challenger – Doubles.
David O'Hare, 7–6(8–6), 6–4