The 2016 San Francisco season is the inaugural season of San Francisco Rush.
| Week | Date | Opponent | Result | Record | Game site | |||
|---|---|---|---|---|---|---|---|---|
| 1 | April 17 | at Sacramento Express | L 25-37 | 0-1 | Bonney Field | |||
| 2 | April 24 | Denver Stampede | L 18-35 | 0-2 | Boxer Stadium | |||
| 3 | May 1 | Ohio Aviators | L 17-51 | 0-3 | EAS Training Center | |||
| 4 | May 8 | San Diego Breakers | L 46-33 | 0-4 | Boxer Stadium | |||
| 5 | Bye | |||||||
| 6 | May 20 | Denver Stampede | L 41-37 | 0-5 | Infinity Park | |||
| 7 | May 29 | Ohio Aviators | W 35-20 | 1-5 | Boxer Stadium | |||
| 8 | Bye | |||||||
| 9 | Bye | |||||||
| 10 | June 18 | at San Diego Breakers | W 19-24 | 2-5 | Torero Stadium | |||
| 11 | June 26 | at Ohio Aviators | L 20 - 71 | 2 - 6 | EAS Training Center | |||
| 12 | July 3 | Sacramento Express | L 19-43 | 2-7 | Boxer Stadium | |||
| 13 | Bye | |||||||
| 14 | July 16 | San Diego Breakers | W 50-26 | 3-7 | Boxer Stadium | |||
| 15 | July 23 | Denver Stampede | L 24-31 | 3-8 | Boxer Stadium | |||
| 16 | July 23 | at Sacramento Express | Bonney Field | |||||