| Champ: |  Federico Gaio |
| Runner: |  Constant Lestienne |
| Score: | 6–2, 1–6, 6–3 |
| Type: | singles doubles |
See main article: 2016 San Benedetto Tennis Cup.
Albert Ramos Viñolas was the defending champion but chose not to participate.
Federico Gaio won the title after defeating Constant Lestienne 6–2, 1–6, 6–3 in the final.