| Date: | 2 – 8 May |
| Edition: | 3rd |
| Draw: | 32S / 15D |
| Surface: | Clay |
| Prize Money: | €85,000+H |
| Location: | Aix-en-Provence, France |
| Champs: |  Thiago Monteiro |
| Champd: |  Oliver Marach / Philipp Oswald |
The 2016 Open du Pays d'Aix was a professional tennis tournament played on clay courts. It was the third edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Aix-en-Provence, France between 2 and 8 May 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Czech Republic | Lukáš Rosol | 65 | 1 | |
 Argentina | Diego Schwartzman | 87 | 2 | |
| Brazil | Rogério Dutra Silva | 101 | 3 | |
 France | Stéphane Robert | 116 | 4 | |
| Mischa Zverev | 129 | 5 | ||
 Sweden | Elias Ymer | 132 | 6 | |
| Daniel Brands | 135 | 7 | ||
| Argentina | Máximo González | 136 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry as a special exempt to gain entry into the main draw:
The following player received entry as a protected ranking to gain entry into the main draw:
The following players received entry from the qualifying draw:
The following players entered as a lucky loser:
See main article: 2016 Open du Pays d'Aix – Singles.
Thiago Monteiro def. Carlos Berlocq, 4–6, 6–4, 6–1See main article: 2016 Open du Pays d'Aix – Doubles.
Oliver Marach / Philipp Oswald def. Guillermo Durán / Máximo González, 6–1, 4–6, [10–7]