| Date: | 12–18 September |
| Edition: | 1st |
| Category: | ITF Women's Circuit |
| Location: | Atlanta, United States |
| Prize Money: | $50,000 |
| Champs: |  Elise Mertens |
| Champd: |  Ingrid Neel /  Luisa Stefani |
The 2016 One Love Tennis Open was a professional tennis tournament played on outdoor hard courts. It was the 1st edition of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $50,000 in prize money. It took place in Atlanta, United States, on 12–18 September 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Belgium | Elise Mertens | 137 | 1 | |
| United States | Taylor Townsend | 146 | 2 | |
| Michaëlla Krajicek | 156 | 3 | ||
| Brazil | Paula Cristina Gonçalves | 160 | 4 | |
 France | Alizé Lim | 180 | 5 | |
| Montserrat González | 192 | 6 | ||
 China | Xu Shilin | 213 | 7 | |
| France | Shérazad Reix | 221 | 8 |
The following player received a wildcard into the singles main draw:
Anna Bright Sophie Chang Julia Elbaba Alexandra SanfordThe following players received entry from the qualifying draw:
Marta González Encinas Brianna Morgan Ingrid Neel Luisa StefaniSee main article: 2016 One Love Tennis Open – Singles.
Elise Mertens def. Melanie Oudin, 6–4, 6–2See main article: 2016 One Love Tennis Open – Doubles.
Ingrid Neel / Luisa Stefani def. Alexandra Stevenson / Taylor Townsend, 4–6, 6–4, [10–5]