Champ: | Karolína Plíšková |
Score: | 7–6(10–8), 7–5 |
Before Year: | 2015 |
See main article: 2016 Nottingham Open.
Ana Konjuh was the defending champion, but withdrew before the tournament began.
Karolína Plíšková won the title, defeating Alison Riske in the final, 7–6(10–8), 7–5.
The top two seeds receive a bye into the second round.