| Champ: |  Steve Johnson |
| Runner: | Pablo Cuevas |
| Score: | 7–6(7–5), 7–5 |
| Main Name: | Nottingham Open |
See main article: 2016 Nottingham Open.
Denis Istomin was the defending champion, but lost in the first round to Damir Džumhur.
Steve Johnson won the title defeating Pablo Cuevas in the final, 7–6(7–5), 7–5.
All seeds receive a bye into the second round.