| Date: | 19–25 September |
| Edition: | 5th |
| Category: | ITF Women's Circuit |
| Location: | Saint Petersburg, Russia |
| Surface: | Hard (indoor) |
| Prize Money: | $100,000 |
| Champs: |  Natalia Vikhlyantseva |
| Champd: | Maria Marfutina / Anna Morgina |
| Before Name: | Kivenappa Ladies' Cup |
The 2016 Neva Cup was a professional tennis tournament played on indoor hard courts. It was the 5th edition[1] of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $100,000 in prize money. It took place in Saint Petersburg, Russia, on 19–25 September 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Turkey | Çağla Büyükakçay | 60 | 1 | |
| Russian Federation | Evgeniya Rodina | 96 | 2 | |
| Donna Vekić | 102 | 3 | ||
| Russian Federation | Irina Khromacheva | 106 | 4 | |
| Richèl Hogenkamp | 136 | 5 | ||
| Russian Federation | Ekaterina Alexandrova | 148 | 6 | |
| Russian Federation | Alla Kudryavtseva | 162 | 7 | |
 Uzbekistan | Sabina Sharipova | 163 | 8 |
The following player received a wildcard into the singles main draw:
Anastasia Bukhanko Maria Marfutina Ksenia Pervak Polina VinogradovaThe following players received entry from the qualifying draw:
Vesna Dolonc
Ilona Kremen Alena Tarasova
Katarina ZavatskaSee main article: 2016 Neva Cup – Singles.
Natalia Vikhlyantseva def. Donna Vekić, 6–1, 6–2See main article: 2016 Neva Cup – Doubles.
Maria Marfutina / Anna Morgina def. 
Raluca Olaru / Alena Tarasova, 6–2, 6–3