| Competition: | MNL-2 |
| Season: | 2016 |
| Winners: | Manaw Myay |
| Runner Up: | GFA |
| Promoted: | Manaw Myay GFA |
| Matches: | 132 |
| Total Goals: | 465 |
| League Topscorer: | Donald Bissa (34 goals) |
| Biggest Home Win: | Nay Pyi Taw 6 - 0 University |
| Biggest Away Win: | University 0 - 7 Manaw Myay |
| Highest Scoring: | Mawyawadi 7 - 3 Silver Stars |
| Best Attacking Team: | Manaw Myay (71 goals) |
| Weak Attacking Team: | United of Thanlyin (21 goals) |
| Best Defence Team: | Mahar United (17 goals) |
| Weak Defence Team: | Silver Stars (72 goals) |
| Prevseason: | 2015 |
| Nextseason: | 2017 |
The MNL-2 2016 is the Myanmar National League's fourth full regular season. Four new clubs will join in 2016 MNL-2. There are Mahar United Football Club (MU FC), United of Thanlyin Football Club, Thihadeepa United Football Club (TU FC) and City Stars Football Club (CS FC). 2016 MNL-2 will start on 15 January. New clubs must play a qualifying round. Only three clubs will qualify to play in MNL-2.
Fixtures and Results of the 2016 MNL-2 season.