The 2016 Italian Open[1] [2] [3] (also known as the 2016 Rome Masters[4] and sponsored title 2016 Internazionali BNL d'Italia) was a tennis tournament played on outdoor clay courts at the Foro Italico in Rome, Italy. It was the 73rd edition of the Italian Open and is classified as an ATP World Tour Masters 1000 event on the 2016 ATP World Tour and a Premier 5 event on the 2016 WTA Tour. It took place from 9 to 15 May 2016.
| Event | Round of 16 | Round of 32 | Round of 64 | width=85 | width=85 | width=85 | |||||||
| Men's singles | 1000 | 600 | 360 | 180 | 90 | 45 | 10 | 25 | 16 | 0 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Men's doubles | 0 | ||||||||||||
| Women's singles | 900 | 585 | 350 | 190 | 105 | 60 | 1 | 30 | 20 | 1 | |||
| Women's doubles | 1 |
| width=130 bgcolor=dfe2e9 | Event | width=80 bgcolor=lime | W | width=85 bgcolor=thistle | F | width=85 bgcolor=ffff00 | SF | width=85 bgcolor=ffebcd | QF | width=85 bgcolor=afeeee | Round of 16 | width=85 bgcolor=afeeee | Round of 32 | width=85 bgcolor=afeeee | Round of 64 | width=85 | Q2 | width=85 | Q1 |
| style=background:#ededed | Men's singles | €717,315 | €351,715 | €177,015 | €90,010 | €46,740 | €24,640 | €13,305 | €3,065 | €1,565 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| style=background:#ededed | Women's singles | €432,100 | €215,950 | €107,860 | €49,680 | €24,630 | €12,645 | €6,500 | €3,620 | €1,860 | |||||||||
| style=background:#ededed | Men's doubles | €222,150 | €108,750 | €54,550 | €28,000 | €14,470 | €7,640 | ||||||||||||
| style=background:#ededed | Women's doubles | €123,700 | €62,470 | €30,920 | €15,565 | €7,860 | €3,895 |
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Serbia | Novak Djokovic | 1 | 1 | |
 United Kingdom | Andy Murray | 2 | 2 | |
| Roger Federer | 3 | 3 | ||
| Stan Wawrinka | 4 | 4 | ||
 Spain | Rafael Nadal | 5 | 5 | |
 Japan | Kei Nishikori | 6 | 6 | |
 France | ||||
 Czech Republic | Tomáš Berdych | 8 | 8 | |
| Spain | David Ferrer | 9 | 9 | |
 Canada | Milos Raonic | 10 | 10 | |
| France | Richard Gasquet | 12 | 11 | |
 Belgium | David Goffin | 13 | 12 | |
 Austria | Dominic Thiem | 14 | 13 | |
| France | Gaël Monfils | 15 | 14 | |
| Spain | Roberto Bautista Agut | 17 | 15 | |
| Kevin Anderson | 19 | 16 |
The following players received wildcards into the main draw:
The following players received entry using a protected ranking into the main draw:
The following players received entry from the qualifying draw:
Aljaž Bedene Íñigo Cervantes
Damir Džumhur
Mikhail Kukushkin Stéphane Robert
Filippo VolandriThe following player received entry as a lucky loser:
Marcos Baghdatis →replaced by Nicolas Mahut Andreas Seppi
Juan Martín del Potro →replaced by Vasek Pospisil Tommy Haas →replaced by Borna Ćorić 
John Isner →replaced by Juan Mónaco
Martin Kližan →replaced by 
Teymuraz Gabashvili Gilles Simon →replaced by Albert Ramos-Viñolas Jo-Wilfried Tsonga (muscle strain) →replaced by Lucas Pouille
Bernard Tomic (influenza)The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
Pierre-Hugues Herbert (knee injury)| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Serena Williams | 1 | 1 | |
| Angelique Kerber | 3 | 2 | ||
| Spain | Garbiñe Muguruza | 4 | 3 | |
 Belarus | Victoria Azarenka | 5 | 4 | |
| Czech Republic | Petra Kvitová | 6 | 5 | |
 Romania | Simona Halep | 7 | 6 | |
| Italy | Roberta Vinci | 8 | 7 | |
| Spain | Carla Suárez Navarro | 11 | 8 | |
| Russian Federation | Svetlana Kuznetsova | 12 | 9 | |
| Czech Republic | Lucie Šafářová | 13 | 10 | |
| Timea Bacsinszky | 15 | 11 | ||
| United States | Venus Williams | 16 | 12 | |
| Serbia | Ana Ivanovic | 17 | 13 | |
| Italy | Sara Errani | 18 | 14 | |
 Ukraine | Elina Svitolina | 19 | 15 | |
| Czech Republic | Karolína Plíšková | 20 | 16 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
Mariana Duque Mariño
Johanna Larsson Christina McHale Alison Riske Heather Watson
Teliana Pereira Camila Giorgi (back injury) → replaced by Caroline Garcia Sloane Stephens → replaced by 
Tímea Babos Yanina WickmayerThe following pairs received wildcards into the doubles main draw:
Claudia Giovine / Angelica Moratelli Karin Knapp / Francesca Schiavone Svetlana Kuznetsova / Anastasia Pavlyuchenkova Serena Williams / Venus Williams Andy Murray def. Novak Djokovic, 6–3, 6–3 Serena Williams def. Madison Keys, 7–6(7–5), 6–3See main article: 2016 Italian Open – Men's doubles.
Bob Bryan / Mike Bryan def. Vasek Pospisil / Jack Sock, 2–6, 6–3, [10–7]
Sania Mirza def. Ekaterina Makarova / Elena Vesnina, 6–1, 6–7(5–7), [10–3]