| Champ: | Stan Wawrinka |
| Runner: | Marin Čilić |
| Score: | 6–4, 7–6(13–11) |
| Draw: | 28 |
| Seeds: | 8 |
| Type: | singles doubles |
See main article: 2016 Geneva Open. Thomaz Bellucci was the defending champion, but lost in the second round to Federico Delbonis.
Stan Wawrinka won the title, defeating Marin Čilić in the final, 6–4, 7–6(13–11).
The top four seeds receive a bye into the second round.