| Year: | 2016 |
| Team: | Duke Blue Devils |
| Sport: | football |
| Conference: | Atlantic Coast Conference |
| Division: | Coastal Division |
| Short Conf: | ACC |
| Record: | 4–8 |
| Conf Record: | 1–7 |
| Head Coach: | David Cutcliffe |
| Hc Year: | 9th |
| Off Coach: | Zac Roper |
| Oc Year: | 1st |
| Off Scheme: | Multiple |
| Def Coach: | Jim Knowles |
| Dc Year: | 7th |
| Def Scheme: | 4–2–5 |
| Mvp: | Daniel Jones |
| Captain: | Jela Duncan, DeVon Edwards, Thomas Sirk, A. J. Wolf |
| Stadium: | Wallace Wade Stadium |
The 2016 Duke Blue Devils football team represented Duke University in the 2016 NCAA Division I FBS football season as a member of the Atlantic Coast Conference (ACC) in the Coastal Division. The team was led by head coach David Cutcliffe, in his ninth year, and played its home games at Wallace Wade Stadium in Durham, North Carolina. They finished the season 4–8 overall and 1–7 in ACC play to tie for sixth place in the Coastal Division.
| Name | Position | Seasons at Duke | Alma Mater | |
|---|---|---|---|---|
| 9th | Alabama (1976) | |||
| 9th | Ole Miss (2001) | |||
| Derek Jones | 9th | Ole Miss (1996) | ||
| Defensive Coordinator/ Inside Linebackers | 6th | Cornell (1987) | ||
| Ben Albert | 1st | Massachusetts (1995) | ||
| Jim Bridge | 1st | Wittenberg (1992) | ||
| Jim Collins | Defensive ends | 8th | Elon (1974) | |
| Offensive line coach | 5th | Ole Miss (2004) | ||
| Matt Guerrieri | 5th | Davidson (2011) | ||
| Running backs | 4th | Duke (2009) | ||
| 5th | Duke (2011) | |||
| Josh Grizzard | Offensive Graduate Assistant | 4th | Yale (2012) | |
| Eli Keimach | Offensive Graduate Assistant | 3rd | Massachusetts (2014) | |
| Clayton McGrath | Defensive tackles/Graduate Assistant | 4th | Brown University (2011) | |
| Sam McGrath | Defensive Graduate Assistant | 2nd | Brown University (2012) | |
| Patrick O'Connor | Defensive Quality Control | 4th | Dickinson College (2010) | |
| Reference:[2] | ||||
See also: 2016 North Carolina Central Eagles football team.
See also: 2016 Wake Forest Demon Deacons football team.
See also: 2016 Northwestern Wildcats football team.
See also: 2016 Notre Dame Fighting Irish football team.
See also: 2016 Virginia Cavaliers football team.
See also: 2016 Army Black Knights football team.
See also: 2016 Louisville Cardinals football team.
See also: 2016 Georgia Tech Yellow Jackets football team.
See also: 2016 Virginia Tech Hokies football team.
See also: 2016 North Carolina Tar Heels football team and Victory Bell (Duke–North Carolina).
See also: 2016 Pittsburgh Panthers football team.
See also: 2016 Miami Hurricanes football team.
No Duke players were selected in the 2017 NFL draft.