| Champ: |  Agnieszka Radwańska |
| Runner: |  Elina Svitolina |
| Score: | 6–1, 7–6(7–3) |
| Draw: | 30 |
| Type: | women |
See main article: article and 2016 Connecticut Open.
Petra Kvitová was the two-time defending champion, but lost in the semifinals to Agnieszka Radwańska.
Radwańska went on to win the title, defeating Elina Svitolina in the final, 6–1, 7–6(7–3).
The top two seeds received a bye into the second round.