| Date: | August 1–7 |
| Edition: | 23rd (men) 5th (women) |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Prize Money: | (men) (women) |
| Surface: | Hard – outdoors |
| Location: | Granby, Quebec, Canada |
| Venue: | Club de tennis des Loisirs de Granby |
| Champms: |  Frances Tiafoe |
| Champws: | Jennifer Brady |
| Champmd: |  Guilherme Clezar /  Alejandro González |
| Champwd: | Jamie Loeb /  An-Sophie Mestach |
| Main Name: | Challenger de Granby |
| After Name: | Challenger de Granby |
The 2016 Challenger Banque Nationale de Granby was a professional tennis tournament played on outdoor hard courts. It was the 23rd edition, for men, and 6th edition, for women, of the tournament and part of the 2016 ATP Challenger Tour and the 2016 ITF Women's Circuit, offering totals of $100,000, for men, and $50,000, for women, in prize money. It took take place in Granby, Quebec, Canada between August 1 and August 7, 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Stéphane Robert | 58 | 1 | |
| France | Quentin Halys | 136 | 2 | |
 India | Saketh Myneni | 152 | 3 | |
| Frances Tiafoe | 157 | 4 | ||
| Colombia | Alejandro González | 163 | 5 | |
| Colombia | Eduardo Struvay | 172 | 6 | |
| France | Vincent Millot | 178 | 7 | |
| France | Grégoire Barrère | 189 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Israel | Julia Glushko | 134 | 1 | |
| Jessica Pegula | 135 | 2 | ||
| Jennifer Brady | 150 | 3 | ||
 Japan | Hiroko Kuwata | 154 | 4 | |
 Czech Republic | Barbora Štefková | 176 | 5 | |
 Belarus | Olga Govortsova | 179 | 6 | |
| Asia Muhammad | 184 | 7 | ||
 Serbia | Jovana Jakšić | 204 | 8 |
The following players received wildcards into the singles main draw:
Bianca Andreescu Marie-Alexandre Leduc Charlotte Robillard-Millette Erin RoutliffeThe following players received entry from the qualifying draw:
Catherine Leduc Nicole Melichar Alexandra Stevenson Jessica WacnikThe following players entered the singles main draw with a protected ranking:
See main article: article and 2016 Challenger Banque Nationale de Granby – Men's singles.
Frances Tiafoe def. Marcelo Arévalo, 6–1, 6–1See main article: article and 2016 Challenger Banque Nationale de Granby – Women's singles.
Jennifer Brady def. Olga Govortsova, 7–5, 6–2See main article: article and 2016 Challenger Banque Nationale de Granby – Men's doubles.
Guilherme Clezar / Alejandro González def. Saketh Myneni / Sanam Singh, 3–6, 6–1, [12–10]See main article: article and 2016 Challenger Banque Nationale de Granby – Women's doubles.
Jamie Loeb / An-Sophie Mestach def. Julia Glushko / Olga Govortsova, 6–4, 6–4
