| Date: | 6–12 June |
| Edition: | 4th |
| Category: | ITF Women's Circuit |
| Location: | Essen, Germany |
| Prize Money: | $50,000 |
| Champs: |  Sara Sorribes Tormo |
| Champd: | Laura Pous Tió / Anne Schäfer |
The 2016 Bredeney Ladies Open was a professional tennis tournament played on outdoor clay courts. It was the fourth edition of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $50,000 in prize money. It took place in Essen, Germany, on 6–12 June 2016.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Belarus | Aliaksandra Sasnovich | 98 | 1 | |
| Carina Witthöft | 100 | 2 | ||
| Spain | Lourdes Domínguez Lino | 112 | 3 | |
| Maria Sakkari | 114 | 4 | ||
 Slovakia | Jana Čepelová | 132 | 5 | |
| Romina Oprandi | 137 | 6 | ||
| Cindy Burger | 173 | 8 |
The following player received a wildcard into the singles main draw:
Kristina Kislyak
Melanie StokkeThe following players received entry from the qualifying draw:
The following players received entry by lucky loser spots:
Sara Sorribes Tormo def. 
Karolína Muchová, 7–6(7–5), 6–4 Laura Pous Tió / Anne Schäfer def. 
Elyne Boeykens / 
Elena Ruse, 6–2, 6–3
