| Champ: |  Bob Bryan Mike Bryan |
| Runner: | Pablo Cuevas  Marcel Granollers |
| Score: | 7–5, 7–5 |
| Type: | singles doubles |
See main article: 2016 Barcelona Open Banc Sabadell.
Marin Draganja and Henri Kontinen were the defending champions, but Draganja chose to compete in Bucharest instead. Kontinen played alongside John Peers, but lost in the first round to Jamie Murray and Bruno Soares.
Bob and Mike Bryan won the title, defeating Pablo Cuevas and Marcel Granollers in the final, 7–5, 7–5.
