The 2016 Bank of the West Classic was a professional tennis tournament played on hard courts. It was the 45th edition of the tournament, and part of the WTA Premier tournaments of the 2016 WTA Tour. It took place in Stanford, California, United States between 18 and 24 July 2016. It was the first women's event on the 2016 US Open Series.
| Event | W | F | SF | QF | Round of 16 | Round of 32 | Round of 64 | width=85 | Q | width=85 | Q2 | width=85 | Q1 |
| Women's singles | 470 | 305 | 185 | 100 | 55 | 30 | 1 | 25 | 13 | 1 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Women's doubles | 1 |
| width=130 bgcolor=dfe2e9 | Event | width=80 bgcolor=lime | W | width=85 bgcolor=thistle | F | width=85 bgcolor=ffff00 | SF | width=85 bgcolor=ffebcd | QF | width=85 bgcolor=afeeee | Round of 16 | width=85 bgcolor=afeeee | Round of 32 | width=85 | Q2 | width=85 | Q1 |
| style=background:#ededed | Women's singles | $128,100 | $68,280 | $37,330 | $21,330 | $10,670 | $6,990 | $3,225 | $1,810 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| style=background:#ededed | Women's doubles | $40,300 | $21,330 | $11,735 | $5,975 | $3,240 |
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Venus Williams | 7 | 1 | ||
 Slovakia | Dominika Cibulková | 12 | 2 | |
 United Kingdom | Johanna Konta | 18 | 3 | |
| CoCo Vandeweghe | 35 | 4 | ||
 Japan | Misaki Doi | 36 | 5 | |
| Jeļena Ostapenko | 37 | 6 | ||
 France | Alizé Cornet | 51 | 7 | |
| Varvara Lepchenko | 52 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Tímea Babos → replaced by Verónica Cepede Royg
Mariana Duque Mariño → replaced by 
Jennifer Brady Naomi Osaka
Daria Kasatkina → replaced by 
Kristýna Plíšková Anastasia Pavlyuchenkova → replaced by 
Urszula Radwańska Agnieszka Radwańska → replaced by Alison Riske
Lesia Tsurenko → replaced by 
Han Xinyun CoCo Vandeweghe (Right ankle injury)| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| China | Xu Yifan | China | Zheng Saisai | 31 | 1 | |
| Raquel Atawo | Abigail Spears | 40 | 2 | |||
| Darija Jurak |  Australia | Anastasia Rodionova | 83 | 3 | ||
| Anna-Lena Grönefeld | Czech Republic | Květa Peschke | 105 | 4 |
The following pair received a wildcard into the main draw:
See main article: 2016 Bank of the West Classic – Singles.
Johanna Konta defeated Venus Williams, 7–5, 5–7, 6–2See main article: 2016 Bank of the West Classic – Doubles.
Raquel Atawo / Abigail Spears defeated Darija Jurak / Anastasia Rodionova, 6–3, 6–4
