| Champ: |  Svetlana Kuznetsova |
| Runner: | Monica Puig |
| Score: | 6–0, 6–2 |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| Main Name: | Sydney International |
See main article: 2016 Apia International Sydney.
Petra Kvitová was the defending champion, but withdrew before her first match due to a gastrointestinal illness.
Svetlana Kuznetsova won the title, defeating Monica Puig in the final, 6–0, 6–2.
The top two seeds received a bye into the second round.