The men's 110 metres hurdles event at the 2016 African Championships in Athletics was held on 24 and 25 June in Kings Park Stadium.[1]
| width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| Antonio Alkana | Tyron Akins | Mohamed Koussi |
Qualification: First 3 of each heat (Q) and the next 2 fastest (q) qualified for the final.
Wind:
Heat 1: +1.8 m/s, Heat 2: +1.3 m/s
| Rank | Heat | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 2 | 13.62 | Q | |||
| 2 | 1 | 13.73 | Q | |||
| 3 | 1 | 13.98 | Q | |||
| 4 | 2 | 14.15 | Q | |||
| 5 | 1 | 14.21 | Q | |||
| 6 | 1 | 14.21 | q | |||
| 7 | 2 | 14.27 | Q | |||
| 8 | 2 | 14.41 | q | |||
| 9 | 2 | 14.52 | ||||
| 10 | 2 | 15.16 | ||||
| 11 | 1 | 15.26 |
Wind: No information
| Rank | Lane | Athlete | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 5 | 13.43 | CR | ||||
| 4 | 13.74 | |||||
| 7 | 13.94 | |||||
| 4 | 6 | 13.99 | ||||
| 5 | 2 | 14.22 | ||||
| 6 | 1 | 14.45 | ||||
| 7 | 3 | 14.52 | ||||
| 8 |