See main article: 2016–17 Women's EHF Champions League. This article describes the main round of the 2016–17 Women's EHF Champions League.
| Group | width=150 | Winners | width=200 | Runners-up | width=160 | Third place |
|---|---|---|---|---|---|---|
| A |  Budućnost |  Metz Handball | Thüringer HC | |||
| B |  HC Vardar |  FTC-Rail Cargo Hungaria |  HC Astrakhanochka | |||
| C | Győri Audi ETO KC |  CSM București | Midtjylland | |||
| D |  Krim |  Larvik HK | Team Esbjerg |
In each group, teams played against each other in a double round-robin format, with home and away matches against teams they did not met before. Points obtained in the group stage were taken over. After completion of the group stage matches, the top four teams of each group advanced to the quarterfinals.[1]
The matchdays were 27–29 January, 3–5 February, 10–12 February, 24–26 February, 3–5 March, 10–12 March 2017.