| Champ: | João Sousa |
| Runner: |  Roberto Bautista Agut |
| Score: | 3–6, 6–3, 6–4 |
| Draw: | 28 |
| Seeds: | 8 |
| Type: | singles doubles |
| After Year: | no |
| Before Name: | Valencia Open 500 |
See main article: 2015 Valencia Open. Andy Murray was the defending champion, but chose not to participate this year.
João Sousa won the title, defeating Roberto Bautista Agut in the final in three sets, 3–6, 6–3, 6–4.
The top four seeds received a bye into the second round.