| Competition: | Campeonato Nacional Apertura Scotiabank |
| Dates: | 25 July 2015– 11 January 2016 |
| Season: | 2015–16 |
| Winners: | Colo-Colo (31st title) |
| Continentalcup1: | 2016 Copa Libertadores |
| Continentalcup1 Qualifiers: | Colo-Colo U. de Chile (Cup winners) |
| Continentalcup2: | 2016 Copa Sudamericana |
| Continentalcup2 Qualifiers: | Universidad Católica |
| League Topscorer: | Marcos Riquelme (11 goals) |
| Biggest Home Win: | Universidad Católica 5–0 O'Higgins (13 September) |
| Highest Attendance: | 37,200 Colo-Colo 1–0 Universidad de Concepción (29 November) |
| Attendance: | 562,365 |
| Average Attendance: | 4,686 |
| Matches: | 120 |
| Total Goals: | 347 |
| Prevseason: | 2015–C |
| Nextseason: | 2016–C |
The 2015 Campeonato Nacional Apertura Scotiabank was the 97th Chilean League top flight, in which Colo-Colo won its 31st league title.
| ANT | AUD | CSA | COL | HUA | IQU | OHI | PAL | SLU | SMA | LCA | UCA | UCH | UCO | UES | SWA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antofagasta | 0–1 | 0–2 | 0–1 | 2–1 | 1–4 | 0–2 | 2–2 | |||||||||
| Audax | 0–0 | 2–2 | 2–1 | 1–1 | 1–0 | 3–1 | 2–1 | 1–1 | ||||||||
| Cobresal | 3–1 | 1–2 | 2–3 | 1–2 | 2–1 | 2–5 | 3–1 | 2–0 | ||||||||
| Colo-Colo | 4–1 | 1–0 | 2–1 | 0–1 | 3–1 | 2–0 | 1–0 | |||||||||
| Huachipato | 1–0 | 2–0 | 1–2 | 2–1 | 0–0 | 1–1 | 0–1 | |||||||||
| Iquique | 1–1 | 2–5 | 0–2 | 2–1 | 2–1 | 1–1 | 0–2 | 5–3 | ||||||||
| O'Higgins | 1–1 | 3–2 | 2–0 | 1–0 | 3–1 | 2–2 | 0–1 | |||||||||
| Palestino | 3–1 | 2–0 | 1–0 | 1–0 | 1–1 | 2–1 | 2–0 | |||||||||
| San Luis | 1–2 | 0–0 | 0–1 | 2–3 | 2–1 | 6–2 | 0–4 | 0–1 | ||||||||
| San Marcos | 0–1 | 1–2 | 2–0 | 0–1 | 0–1 | 4–1 | 1–1 | |||||||||
| La Calera | 2–0 | 1–2 | 0–2 | 1–0 | 0–2 | 1–4 | 1–0 | |||||||||
| U. Católica | 2–1 | 5–0 | 2–0 | 1–0 | 5–1 | 3–1 | 2–1 | |||||||||
| U. Chile | 1–1 | 2–1 | 4–4 | 4–2 | 2–2 | 1–1 | 0–1 | |||||||||
| U. Concepción | 3–1 | 2–0 | 1–1 | 3–1 | 1–0 | 1–0 | 1–2 | 4–1 | ||||||||
| U. Española | 3–2 | 1–2 | 2–2 | 3–0 | 1–2 | 4–0 | 2–0 | 2–4 | ||||||||
| S. Wanderers | 2–1 | 3–1 | 2–2 | 1–1 | 3–0 | 2–2 | 1–2 | 1–2 | ||||||||
| Pos | Team | GP | W | D | L | GF | GA | GD | Pts | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | align=left | Colo-Colo | 15 | 11 | 0 | 4 | 24 | 14 | +10 | 33 | |
| 2 | align=left | Universidad Católica | 15 | 10 | 2 | 3 | 33 | 15 | +18 | 32 | |
| 3 | align=left | Universidad de Concepción | 15 | 9 | 1 | 5 | 29 | 19 | +10 | 28 | |
| 4 | align=left | Palestino | 15 | 8 | 4 | 3 | 23 | 17 | +6 | 28 | |
| 5 | align=left | Audax Italiano | 15 | 7 | 5 | 3 | 22 | 19 | +3 | 26 | |
| 6 | align=left | Unión Española | 15 | 7 | 3 | 5 | 30 | 20 | +10 | 24 | |
| 7 | align=left | O'Higgins | 15 | 7 | 2 | 6 | 23 | 23 | 0 | 23 | |
| 8 | align=left | Santiago Wanderers | 15 | 5 | 5 | 5 | 20 | 19 | +1 | 20 | |
| 9 | align=left | Cobresal | 15 | 6 | 0 | 9 | 23 | 28 | -5 | 18 | |
| 10 | align=left | San Marcos de Arica | 15 | 5 | 2 | 8 | 18 | 20 | -2 | 17 | |
| 11 | align=left | Universidad de Chile | 15 | 4 | 5 | 6 | 24 | 30 | -6 | 17 | |
| 12 | align=left | Huachipato | 15 | 4 | 4 | 7 | 16 | 21 | -5 | 16 | |
| 13 | align=left | Deportes Iquique | 15 | 4 | 4 | 7 | 20 | 28 | -8 | 16 | |
| 14 | align=left | Unión La Calera | 15 | 4 | 3 | 8 | 13 | 27 | -14 | 15 | |
| 15 | align=left | San Luis | 15 | 4 | 1 | 10 | 18 | 24 | -6 | 13 | |
| 16 | align=left | Deportes Antofagasta | 15 | 2 | 5 | 8 | 11 | 23 | -12 | 11 |
| bgcolor=gold style="width: 20px;" | Champions and qualified for the 2016 Copa Libertadores | ||
| bgcolor=#ccffff style="width: 20px;" | Qualified for the Liguilla Pre-Copa Sudamericana |
Following the conclusion of the regular season, the teams placed 2nd to 5th advanced to the Liguilla in order to determine the "Chile 1" spot to the 2016 Copa Sudamericana.
Universidad Católica won 3–2 on aggregate.----
Palestino won 3–1 on aggregate.
Universidad Católica won 5–3 on aggregate and qualified for the 2016 Copa Sudamericana.