| Date: | 27 April – 2 May |
| Edition: | 16th |
| Draw: | 32S / 16D |
| Surface: | Green clay |
| Prize Money: | $50,000 |
| Location: | Tallahassee, Florida, United States |
| Champs: |  Facundo Argüello |
| Champd: |  Dennis Novikov / Julio Peralta |
The 2015 Tallahassee Tennis Challenger was a professional tennis tournament played on green clay courts. It was the 16th edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Tallahassee, Florida, United States between April 27 and May 2, 2015.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Argentina | Facundo Bagnis | 90 | 1 | |
| Austin Krajicek | 116 | 2 | ||
 Canada | Frank Dancevic | 141 | 3 | |
 Australia | Jason Kubler | 152 | 4 | |
| Argentina | Facundo Argüello | 164 | 5 | |
| Bjorn Fratangelo | 165 | 6 | ||
 India | Somdev Devvarman | 168 | 7 | |
 Ireland | James McGee | 169 | 8 |
The following players received wildcards into the singles main draw:
Jean-Yves Aubone Stefan Kozlov Tommy PaulThe following players received entry from the qualifying draw:
Facundo Bagnis Sekou Bangoura Mico Santiago
Jose Rubin Statham| Country | Player | Country | Player | Rank | Seed | |
|---|---|---|---|---|---|---|
 United Kingdom | Ken Skupski | United Kingdom | Neal Skupski | 253 | 1 | |
| Kevin King | Dean O'Brien | 373 | 2 | |||
| Argentina | Guillermo Durán | Argentina | Renzo Olivo | 376 | 3 | |
| James Cerretani | Canada | Frank Dancevic | 399 | 4 |
The following pairs received wildcards into the doubles main draw:
Marco Aurelio Núñez Stefan Kozlov / Rhyne Williams Terrell Whitehurst / Terrence Whitehurst Facundo Argüello def. Frances Tiafoe, 2–6, 7–6(7–5), 6–4 Dennis Novikov / Julio Peralta def. Somdev Devvarman / Sanam Singh, 6–2, 6–4