| Date: | 5–10 May |
| Edition: | 8th |
| Surface: | Clay |
| Location: | Cali, Colombia |
| Champs: |  Fernando Romboli |
| Champd: | Marcelo Demoliner /  Miguel Ángel Reyes-Varela |
The 2015 Seguros Bolívar Open Cali was a professional tennis tournament played on clay courts. It was the eighth edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Cali, Colombia between 4 and 10 May 2015.
| Country | Player | Rank | Seed | |
|---|---|---|---|---|
| Blaž Rola | 93 | 1 | ||
 Belgium | Niels Desein | 161 | 2 | |
| Chase Buchanan | 163 | 3 | ||
| Nicolás Jarry | 183 | 4 | ||
 Argentina | Guido Andreozzi | 204 | 5 | |
 Sweden | Christian Lindell | 222 | 6 | |
| Argentina | Juan Ignacio Londero | 235 | 7 | |
 Dominican Republic | José Hernández | 240 | 8 |
The following players received wildcards into the singles main draw:
José Carvajal Daniel Elahi Galán Felipe Mantilla
David SoutoThe following players used protected ranking to gain into the singles main draw:
The following players received entry from the qualifying draw:
Gonzalo Escobar Fernando Romboli Wilson Leite Nicolas Santos| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Brazil | Marcelo Demoliner | Mexico | Miguel Ángel Reyes-Varela | 250 | 1 | |
| Ruben Gonzales |  United Kingdom | Darren Walsh | 329 | 2 | ||
| Nicolás Jarry | Mexico | César Ramírez | 334 | 3 | ||
| Kevin King | Dean O'Brien | 344 | 4 |
The following pairs received wildcards into the singles main draw:
Juan Sebastián Gómez / Nicolás Kicker José Daniel Bendeck / Alejandro Gómez Carlos Salamanca / David SoutoSee main article: 2015 Seguros Bolívar Open Cali – Singles.
Fernando Romboli def. Giovanni Lapentti, 4–6, 6–3, 6–2See main article: 2015 Seguros Bolívar Open Cali – Doubles.
Marcelo Demoliner / Miguel Ángel Reyes-Varela def. Emilio Gómez / Roberto Maytín, 6–1, 6–2