| Date: | 27 October – 1 November |
| Edition: | 2nd |
| Category: | ITF Women's Circuit |
| Location: | Nanjing, China |
| Prize Money: | $100,000 |
| Champs: | Hsieh Su-wei |
| Champd: |  Shuko Aoyama / Eri Hozumi |
| Before Year: | 2013 |
The 2015 Nanjing Ladies Open was a professional tennis tournament played on outdoor hard courts. It was the second edition of the tournament and part of the 2015 ITF Women's Circuit, offering a total of $100,000 in prize money. It took place in Nanjing, China, on 27 October to 1 November 2015.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 China | Zheng Saisai | 75 | 1 | |
| Japan | Nao Hibino | 78 | 2 | |
| Japan | Kurumi Nara | 83 | 3 | |
 Kazakhstan | Yulia Putintseva | 84 | 4 | |
 Russian Federation | Elizaveta Kulichkova | 99 | 5 | |
| China | Wang Qiang | 106 | 6 | |
| China | Duan Yingying | 114 | 7 | |
| Hsieh Su-wei | 120 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2015 Nanjing Ladies Open – Singles.
Yulia Putintseva, 7–6(7–5), 2–6, 6–2See main article: 2015 Nanjing Ladies Open – Doubles.
Shuko Aoyama / Eri Hozumi def. Chan Chin-wei / Zhang Kailin, 7–5, 6–7(7–9), [10–7]