The 2015 Internazionali di Tennis Città di Vicenza was a professional tennis tournament played on clay courts. It was the second edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Vicenza, Italy between 25 and 31 May May 2015.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Argentina | Facundo Bagnis | 95 | 1 | |
 Slovakia | Norbert Gombos | 105 | 2 | |
 United Kingdom | James Ward | 106 | 3 | |
| Argentina | Guido Pella | 114 | 4 | |
 Spain | Albert Montañés | 129 | 5 | |
 Australia | John Millman | 133 | 6 | |
| Thiemo de Bakker | 134 | 7 | ||
| Bjorn Fratangelo | 147 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as special exempt:
The following players received entry from the qualifying draw:
See main article: 2015 Internazionali di Tennis Città di Vicenza – Singles.
Íñigo Cervantes def. John Millman 6–4, 6–2See main article: 2015 Internazionali di Tennis Città di Vicenza – Doubles.
Facundo Bagnis / Guido Pella def. 
Salvatore Caruso / Federico Gaio 6–2, 6–4
