See main article: 2015 Internationaux de Strasbourg. The singles tennis tournament at the 2015 Internationaux de Strasbourg took place in Strasbourg, France, as part of the 2015 WTA Tour.
Monica Puig was the defending champion, but lost in the first round to Samantha Stosur. Third-seeded Stosur went on to win the title, defeating Kristina Mladenovic in the final, 3–6, 6–2, 6–3.
The top two seeds and Océane Dodin received a bye into the qualifying competition.