The men's 4x100 metres relay at the 2015 IPC Athletics World Championships was held at the Suheim Bin Hamad Stadium in Doha from 22–31 October.
| T11-13[1] | Fedor Trikolich (T12) Aleksei Labzin (T13) Artem Loginov (T12) Andrey Koptev (T11) Guide: Sergey Petrchenko | 42.11 WR | Miran Sahatov (T11) Guide: Valentin Bulichev Mansur Abdirashidov (T12) Ulugbek Chariev (T12) Fakhriddin Khamraev (T13) | 43.71 NR | Martin Parejo Maza (T11) Guide: Timoteo Stewart Ortiz Diego Sancho Villanueva (T13) Gerard Descarrega Puigdevall (T11) Guide: Marcos Blanquino Exposito Joan Munar Martinez(T12) | 44.24 | |
| T42-47[2] | Markus Rehm (T44) David Behre (T43) Felix Streng (T44) Johannes Floors (T43) | 41.86 AR | Trenten Merrill (T44) David Prince (T44) Roderick Townsend-Roberts (T46) Richard Browne (T44) | 42.91 SB | Anton Prokhorov (T42) Alexey Kotlov (T47) Vadim Trunov (T47) Vadim Aleshkin(T44) | 44.27 NR | |