| Year: | 2015 |
| Team: | Eastern Illinois Panthers |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Statsrank: | 25 |
| Fcscoachrank: | 24 |
| Record: | 7–5 |
| Conf Record: | 7–1 |
| Head Coach: | Kim Dameron |
| Hc Year: | 2nd |
| Off Coach: | Greg Stevens |
| Oc Year: | 2nd |
| Def Coach: | Kane Wommack |
| Dc Year: | 2nd |
| Stadium: | O'Brien Field |
| Bowl: | NCAA Division I First Round |
| Bowl Result: | L 17–53 vs. Northern Iowa |
The 2015 Eastern Illinois Panthers football team represented Eastern Illinois University as a member of the Ohio Valley Conference (OVC) during the 2015 NCAA Division I FCS football season. Led by second-year head coach Kim Dameron, the Eastern Illinois compiled an overall record of 7–5 overall with a mark of 7–1 in conference play, placing second in the OVC. The Panthers received an at-large bid to the NCAA Division I Football Championship playoffs, where they lost in the first round to Northern Iowa. The team played home games at O'Brien Field in Charleston, Illinois.