See main article: 2015 Dubai Tennis Championships.
Simona Halep defeated Karolína Plíšková in the final, 6–4, 7–6(7–4) to win the women's singles tennis title at the 2015 Dubai Tennis Championships.
Venus Williams was the defending champion, but lost in the third round to Lucie Šafářová.
The top eight seeds received a bye into the second round.
The two Antwerp finalists also received a bye into the second round. They were as follows: