| Date: | 21–27 September |
| Edition: | 1st |
| Draw: | 32S / 16D |
| Surface: | Hard / Indoors |
| Prize Money: | $50,000 |
| Location: | Columbus, United States |
| Champs: |  Dennis Novikov |
| Champd: | Chase Buchanan / Blaž Rola |
| After Name: | Columbus Challenger 1 |
The 2015 Columbus Challenger was a professional tennis tournament played on indoor hard courts. It was the first edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Columbus, United States between 21 and 27 September 2015.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Tim Smyczek | 107 | 1 | |
 Australia | John-Patrick Smith | 111 | 2 | |
| United States | Bjorn Fratangelo | 118 | 3 | |
| United States | Ryan Harrison | 129 | 4 | |
| United States | Austin Krajicek | 130 | 5 | |
| Blaž Rola | 139 | 6 | ||
 United Kingdom | Brydan Klein | 178 | 7 | |
| United States | Dennis Novikov | 208 | 8 |
No Wild Cards were distributed for this event.
The following players received entry into the singles main draw courtesy of a protected ranking:
Dennis Nevolo
Peter PolanskyThe following players received entry from the qualifying draw:
Hugo Di Feo Peter KobeltSee main article: 2015 Columbus Challenger – Singles.
Dennis Novikov def. Ryan Harrison, 6–3, 3–6, 6–3See main article: 2015 Columbus Challenger – Doubles.
Chase Buchanan / Blaž Rola def. Mitchell Krueger / Eric Quigley, 6–4, 4–6, [19–17]