| Date: | 20 – 26 April |
| Edition: | 5th |
| Draw: | 32S / 16D |
| Surface: | Clay |
| Prize Money: | $50,000 |
| Location: | Santos, Brazil |
| Champd: |  Máximo González /  Roberto Maytín |
The 2015 Campeonato Internacional de Tenis de Santos was a professional tennis tournament played on clay courts. It was the fifth edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Santos, Brazil between 20 and 26 April 2015.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Argentina | Máximo González | 115 | 1 | |
| Blaž Rola | 103 | 2 | ||
 Brazil | André Ghem | 151 | 3 | |
| Argentina | Guido Pella | 156 | 4 | |
| Chase Buchanan | 168 | 5 | ||
| Brazil | Guilherme Clezar | 182 | 6 | |
| Nicolás Jarry | 196 | 7 | ||
| Argentina | Guido Andreozzi | 201 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received an entry as a lucky loser:
See main article: 2015 Campeonato Internacional de Tenis de Santos – Singles.
Germain Gigounon, 6–3, 3–6, 6–3See main article: 2015 Campeonato Internacional de Tenis de Santos – Doubles.
Máximo González / Roberto Maytín def. Andrés Molteni / Guido Pella, 6–4, 7–6(7–4)