| Champ: |  Maria Sharapova |
| Runner: |  Ana Ivanovic |
| Score: | 6–7(4–7), 6–3, 6–3 |
| Draw: | 30 |
| Seeds: | 8 |
See main article: 2015 Brisbane International.
Serena Williams was the two-time defending champion, but she chose to participate at the Hopman Cup instead.
Maria Sharapova won the title, defeating Ana Ivanovic in the final 6–7(4–7), 6–3, 6–3.
The top two seeds receive a bye into the second round.