The 2015–16 Southern Combination Football League season was the 91st in the history of the competition (the first since it changed name from the Sussex County Football League), a football league in England. This is also the first season in which all divisions were renamed after league restructuring.
| Competition: | Southern Combination Premier Division |
| Season: | 2015–16 |
| Winners: | Horsham |
| Promoted: | Horsham |
| Relegated: | East Preston St Francis Rangers |
| Matches: | 380 |
| Total Goals: | 1585 |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
The Premier Division featured 16 clubs which competed in the Sussex County League Division One last season, along with four new clubs:
Six clubs have applied for promotion to Step 4: Eastbourne Town, Horsham, Horsham YMCA, Lancing, Loxwood and Newhaven.[1]
| Competition: | Southern Combination Division One |
| Season: | 2015–16 |
| Winners: | Haywards Heath Town |
| Promoted: | Haywards Heath Town Crawley Down Gatwick |
| Matches: | 272 |
| Total Goals: | 1075 |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
Division One featured ten clubs which competed in the Sussex County League Division Two last season, along with seven new clubs.
Relegation from this division was not implemented for this season.
| Competition: | Southern Combination Division Two |
| Season: | 2016–17 |
| Winners: | AFC Varndeanians |
| Promoted: | AFC Varndeanians Billingshurst |
| Relegated: | Hurstpierpoint |
| Matches: | 240 |
| Total Goals: | 1004 |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
Division Two featured eight clubs which competed in the Sussex County League Division Three last season, along with eight new clubs.
In addition, Burgess Hill & Hurst Albion split and reverted to their original names of Hurstpierpoint (remaining in this league) and Burgess Hill Albion (joining the Mid Sussex League), while Ifield changed its name to Ifield Galaxy.
Promotion and relegation to and from this division was irregular, due to ground grading issues and other league constitution aspects.