| Mode: | Basketball |
| Year: | 2015–16 |
| Team: | Penn Quakers |
| Conference: | Ivy League |
| Short Conf: | Ivy |
| Record: | 11–17 |
| Conf Record: | 5–9 |
| Hc Year: | 1st |
| Asst Coach1: | Nat Graham |
| Asst Coach3: | Joe Mihalich, Jr. |
The 2015–16 Penn Quakers men's basketball team represented the University of Pennsylvania during the 2015–16 NCAA Division I men's basketball season. The Quakers, led by first year head coach Steve Donahue, played their home games at The Palestra and were members of the Ivy League. They finished the season 11–17, 5–9 in Ivy League play to finish in fifth place.
The Quakers finished the season 9–19, 4–10 in Ivy League play to finish in a tie for seventh place.
| Name | Number | Pos. | Height | Weight | Year | Hometown | Notes | |
|---|---|---|---|---|---|---|---|---|
| Camyrn Crocker | 15 | G | 6'3" | 170 | Senior | Graduated | ||
| Greg Louis | 23 | F | 6'7" | 215 | Senior | Graduated | ||
| Patrick Lucas-Perry | 30 | G | 5'11" | 165 | Senior | Graduated | ||
| Preston Troutt | 32 | G | 5'11" | 165 | Sophomore | Left the team for personal reasons |
|-!colspan=9 style="background:#95001A; color:#01256E;"| Regular season[1]