| Club: | MSV Duisburg |
| Season: | 2015–16 |
| Manager: | Gino Lettieri |
| League: | 2. Bundesliga |
| League Result: | 16th place (relegated) |
| Cup1: | DFB-Pokal |
| Cup1 Result: | First round |
| League Topscorer: | Giorgi Chanturia Kingsley Onuegbu (4) |
| Season Topscorer: | Giorgi Chanturia Kingsley Onuegbu (4) |
| Highest Attendance: | 30,600 |
| Lowest Attendance: | 12,509 |
| Average Attendance: | 19,240 |
| Pattern La1: | _duisburg1112h |
| Pattern B1: | _white_hoops |
| Pattern Ra1: | _duisburg1112h |
| Leftarm1: | 0000FF |
| Body1: | 0000FF |
| Rightarm1: | 0000FF |
| Shorts1: | FFFFFF |
| Socks1: | FFFFFF |
| Pattern La2: | _black_hoops |
| Pattern B2: | _hoops_black |
| Pattern Ra2: | _black_hoops |
| Leftarm2: | 555555 |
| Body2: | 555555 |
| Rightarm2: | 555555 |
| Shorts2: | 000000 |
| Socks2: | 000000 |
| Leftarm3: | FF6F00 |
| Body3: | FF6F00 |
| Rightarm3: | FF6F00 |
| Shorts3: | FFFF00 |
| Socks3: | FFFF00 |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
The 2015–16 MSV Duisburg season was the 116th season in the club's football history. In 2015–16 the club played in the 2. Bundesliga, the second tier of German football after being promoted.
The preseason started on 15 June 2015.[1]
See main article: article and 2015–16 DFB-Pokal.
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| Rank | Player | Position | 2. Bundesliga | DFB-Pokal | Total | ||
|---|---|---|---|---|---|---|---|
| align=center rowspan=2 | 1 |  Giorgi Chanturia | 4 | 0 | align=center rowspan=2 | 4 | |
 Kingsley Onuegbu | 4 | 0 | |||||
| align=center rowspan=5 | 3 | Steffen Bohl | 3 | 0 | align=center rowspan=5 | 3 | |
| Thomas Bröker | 3 | 0 | |||||
| Stanislav Iljutcenko | 3 | 0 | |||||
| Victor Obinna | 3 | 0 | |||||
| Kevin Wolze | 3 | 0 | |||||
| align=center rowspan=2 | 8 |  Rolf Feltscher | 2 | 0 | align=center rowspan=2 | 2 | |
| Nico Klotz | 1 | 0 | |||||
| align=center rowspan=5 | 10 | Tim Albutat | 1 | 0 | align=center rowspan=5 | 1 | |
 Branimir Bajić | 1 | 0 | |||||
| Zlatko Janjić | 1 | 0 | |||||
| Thomas Meißner | 1 | 0 | |||||
| Kevin Scheidhauer | 1 | 0 | |||||
| align=center colspan=3 | Total | 33 | 0 | 33 |