See main article: 2015–16 Eurocup Basketball. The 2015–16 Eurocup Basketball knockout stage was played from 23 February to 27 April 2016. A total of 16 teams compete in the knockout stage.
In the knockout stage, teams played against each other over two legs on a home-and-away basis, with the overall cumulative score determining the winner of a round. Thus, the score of one single game can be tied.
| Group | width=220 | Winners (Seeded in eighthfinals) | width=220 | Runners-up (Unseeded in eighthfinals) |
|---|---|---|---|---|
| G | Bayern Munich |  Banvit | ||
| H |  Herbalife Gran Canaria |  SIG Strasbourg | ||
| I | EWE Baskets Oldenburg | Limoges CSP | ||
| J |  EA7 Emporio Armani Milan | Alba Berlin | ||
| K | Dolomiti Energia Trento | Pınar Karşıyaka | ||
| L |  Zenit Saint Petersburg |  Stelmet Zielona Góra | ||
| M | UNICS | Nizhny Novgorod | ||
| N | Galatasaray Odeabank | CAI Zaragoza |
The first legs were played on 24 February, and the second legs were played on 1 and 2 March 2016.|}
The first legs were played on 15 and 16 March, and the second legs were played on 22 and 23 March 2016.|}
The first legs were played on 29 and 30 March, and the second legs were played on 6 April 2016.
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See main article: 2016 Eurocup Finals.
The first leg was played on 22 April, and the second leg was played on 27 April 2016.
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