| Competition: | Antigua and Barbuda Premier Division |
| Season: | 2015 - 16 |
| Relegated: | Fort Road Five Islands |
| Continentalcup1: | CFU Club Championship |
| Continentalcup1 Qualifiers: | Hoppers Grenades |
| Biggest Home Win: | Parham 7–0 Five Islands |
| Biggest Away Win: | Fort Road 1–4 Grenades |
| Highest Scoring: | Fort Road 3–6 Ottos Rangers |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
The 2015–16 Antigua and Barbuda Premier Division was the 45th season of the competition. Hoppers won the title.